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Additionally, administration of varenicline to pregnant rats during organogenesis through lactation produced developmental toxicity in offspring at maternal exposures equivalent to 36 times human exposure at the MRHD [see Data ]

Fission is mediated by the recruitment of Drp1 from the cytosol to the outer membrane, forming a contractile ring, which cleaves the mitochondrion (Los n et al., 2013)

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Fibrosis Fibrosis is the accumulation of scar tissue as a result of damage or bacterial infection